Rosuvastatin is a cholesterol-lowering medication used to prevent cardiovascular disease in individuals at high risk and to treat abnormal lipid levels, such as high LDL cholesterol and triglycerides. It is most effective when combined with healthy lifestyle changes including diet, exercise, and weight management. Rosuvastatin is taken orally and belongs to the statin class, working by inhibiting the enzyme HMG-CoA reductase, which is responsible for cholesterol production in the liver. Common side effects may include headache, abdominal pain, nausea, and muscle pain, while serious effects can include liver damage, rhabdomyolysis, and increased blood sugar levels.

Aspirin is an antiplatelet agent that helps reduce the risk of heart attacks and strokes by preventing the formation of blood clots. It works by inhibiting cyclooxygenase (COX) enzymes, which play a role in platelet aggregation. Aspirin does not lower cholesterol but complements rosuvastatin by reducing clot-related risks, making the combination useful for patients with multiple cardiovascular risk factors. It is commonly prescribed for secondary prevention in individuals with a history of heart disease or stroke.

The combination of rosuvastatin 10 mg and aspirin 75 mg is typically used in patients with established atherosclerotic cardiovascular disease or those with high-risk conditions such as diabetes, hypertension, or elevated cholesterol. This dual therapy targets both cholesterol management and clot prevention, thereby offering a comprehensive approach to reducing the risk of serious cardiovascular events. The combination should only be used under medical supervision, as both drugs carry risks when not properly monitored.

Potential side effects from this combination include gastrointestinal discomfort, constipation, bleeding tendency, and muscle-related symptoms. Serious risks may include gastrointestinal bleeding from aspirin or muscle breakdown and liver issues from rosuvastatin. This medication is not recommended during pregnancy or breastfeeding. Patients should inform their doctor about any other medications, medical conditions, or allergies before starting treatment to avoid harmful interactions or complications.